Friday 18^th March 2016

13:30      Welcome and introduction (D. Betticher, Fribourg)

Concepts of Immune regulations and clinical trials, part 1 (R. Stahel)

14:00      Mechanisms and regulation of T-cell responses, including tumor antigeneicity (N. Rufer, Lausanne)

14:30      Combinations of various immunotherapy approaches (immuno-immuno), with anti angiogenesis (immuno-angio) and radiation (immuno-radio) (G. Coukos, Lausanne)

15:00      Discussion and questions on concepts

15.30      Coffee break

Concepts of Immune regulations and clinical trials, part 2 (O. Michielin)

16:00      Biology of the PD-1 pathway (A. Ochsenbein, Bern)

16:30      Combinations with cytotoxics, targeted agents and molecular therapy (A. Zippelius, Basel)

17:00      Discussion and questions on concepts

Melanoma (D. Betticher)

17:30      Case presentation (O. Michielin, Lausanne)

17:45      Immunotherapy in Melanoma (O. Michielin, Lausanne)

18:15      Adjourn

Saturday 19^th March 2016

Statistics (R. Stahel)

08:00      Statistical approach to immunotherapy trials (U. Dafni, Athens)

NSCLC (R. Stahel)

08:30      Case presentation (A. Curioni, Zürich)

08:45      Immunotherapy in lung cancer (S. Peters, Lausanne)

Myleoma/Lymphoma / Hodgkin's disease (R. Stahel)

09:15      Case presentation (R. Schwotzer, Zürich)

09:30      Immunotherapy in lymphoma / hodgkin (S. Balabanov, Zürich)

10:00 Coffee Break

Urogenital cancer (S. Peters)

10:30      Case presentation (E. Pardo, Luzern)

10:45      Immunotherapy in urogenital cancer (F. Stenner, Basel)

Colorectal cancer (S. Peters)

11:15      Case presentation (M. Montemurro, Lausanne)

11:30      Immunotherapy in colorectal cancer and other tumors of GI (M. Montemurro, Lausanne)

Head and neck cancer (S. Peters)

12:00      Case presentation (D. Weiler, Luzern)

12:15      Immunotherapy in head and neck cancer (S. Rothschild, Basel)

12:45      Conclusion and wrap-up (D. Betticher, Fribourg)